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Why Everyone Needs Fruitflow® for healthy circulation

Fruitflow® is a first natural, scientifically-substantiated solution water-soluble tomato concentrate that helps maintain normal platelet aggregation contributing to healthy blood flow[1].  

Fruitflow® harnesses the anti-platelet compounds of tomato fruit, which helps maintain normal platelet aggregation, which contributes to healthy blood flow. This natural, healthy and safe ingredient can be used in food, beverage and dietary supplement applications.

There is evidence to suggest that people consuming a Mediterranean diet enjoy a degree of cardio protection[2], as it was observed that coronary heart disease caused fewer deaths in Mediterranean countries, such as Greece and Italy, than in the US and Northern Europe. A Mediterranean diet is rich in the consumption of tomatoes, and it has been shown that certain parts of the tomato fruit have antiplatelet properties which modulate blood clotting, therefore reducing the risk of thrombotic events in high-risk cardiovascular disease patients, and may also be beneficial in primary prevention of cardiovascular disease[3].

Platelets found in the blood patrol the vascular system and become activated when damage occurs to blood vessels so that they may prevent blood loss. They do this by sticking together in order to repair any damage. However, platelets can become hyperactive, due to ageing, smoking, conditions such as diabetes and hyperlipidaemia and sedentary lifestyles. Hyperactive platelets are involved in the development of atherosclerosis as they have a tendency to become ‘sticky’.

Fruitflow® is a water-soluble, tomato-based concentrated containing many active ingredients, such as nucleosides, polyphenols and flavonoids which help keep the blood flowing smoothly to help maintain a healthy heart and cardiovascular system.

Aspirin is often prescribed or taken to reduce platelet aggregation. However, aspirin will result in total and irreversible inhibition of platelet aggregation, which is why bleeding complications can sometimes occur[4]. Fruitflow® slows the reactions of platelets down, whilst still allowing them to clot normally.

Fruitflow® can help maintain healthy blood flow by smoothing platelets in the blood minimising a part of the mechanism by which Deep vein thrombosis (DVT) arises. Inactivity from sitting down for long periods of time, either on long journeys, working in an office or from home, can cause the blood to collect in the lower parts of the body, often the lower legs, and this slow blood flow can increase the chances of a blood clot forming. For people predisposed to Deep vein thrombosis (DVT) caused by a blood clot in the circulatory system, Fruitflow® should be included in their daily supplementation.

Other benefits of Fruitflow®

Fruitflow® has significant anti-inflammatory properties[5], which means it may be able to down-regulate the inflammatory pathway involved in atherosclerosis, a chronic inflammatory disease of the arterial vessel, which is the most common cause of cardiovascular disease.

Hypertension is another very important risk factor for CVD including coronary heart disease, stroke, congestive heart failure and peripheral vascular disease. Polyphenols which can be found in Fruitflow® have been shown to increase vasodilation in blood vessels, therefore lowering blood pressure.

The growing evidence from the studies carried out on Fruitflow® suggests that supplementation can help people reduce the risks associated with poor blood flow. A reduction in blood pressure is achievable with a dosage of 150mg of Fruitflow® daily[6].


[1] O’Kennedy, N. Raederstorff, D. Duttaroy, A. (2016) ‘FruitFlow® the first European Food Safety Authority-approved natural cardio-protective functional ingredient’ European Journal of Nutrition 394:1-22.

[2] Estruch, R. Ros, E. Salas-Salvado, J. et al. (2013) ‘Primary prevention of cardiovascular disease with a Mediterranean diet’ New England Journal of Medicine 368:1279-1290.

[3] Kaplan, Z. Jackson, S. (2011) ‘The role of platelets in atherothrombosis’ The American Society of Hematology 2011:51-61.

[4] O’Kennedy, N. Crosbie, L. Song, H. et al. (2016) ‘A randomised controlled trial comparing a dietary an antiplatelet, the water-soluble tomato extract Fruitflow®, with 75mg aspirin in healthy subjects’ European Journal of Clinical Nutrition 71:723-730.

[5] Schwager, J. Richard, N. Mussler, B. et al. (2016) ‘Tomato extract modulates the inflammatory profile of immune cells and endothelial cells’ Molecules 21(2):168.

[6] Uddin, M. Biswas, D. Ghosh. A. et al. (2018) ‘Consumption of Fruitflow® lowers blood pressure in pre-hypertensive males: a randomised, placebo controlled, double blind, cross-over study’ International Journal of Food Science & Nutrition 69(4):494-502.